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. 2016 Nov 15;10:111. doi: 10.3389/fnana.2016.00111

Figure 4.

Figure 4

Beta III tubulin (TUBB3) immunoreactivity in an overview image of the fetal inner ear at W12. The immunoreactivity is apparent in the nerve fibers innervating the ampullary organs (ant, anterior; horiz, horizontal; post, posterior cristae) and the macular organs (U, utricle; S, saccule) of the vestibule. The singular nerve (sing.N) as well as the nerve fibers of both the vestibular ganglia (VG inf., Vestibular ganglion inferior; VG sup., Vestibular ganglion superior) are immunoreactive for Beta III tubulin. Inset exhibits the stained fibers intermingling with the base of the hair cells. The fibers extending from the base to apex of the future Organ of Corti are also positive for this marker. The nerve fibers are also apparent at the apical turn (at), middle turn (mt), and the basal turn (bt). The nerve fibers of the spiral ganglion (sg) distinctly express TUBB3. The somata of the sg also exhibit TUBB3. Scale bar: 50 μm.