Table 2.
Geometric means (95%CI) of immunological markers determined in schoolchildren by STH infection status (n = 224)a.
| Parameter | Nonparasitized | Ascariasis | Trichuriasis | Mix infections |
|---|---|---|---|---|
| n = 178 | n = 17 | n = 21 | n = 29 | |
| Eosinophils (cells/µL) | 273.5 (240.7–310.8) | 320.8 (229.7–448.0) | 410.1 (277.1–606.9)∗ | 448.9 (292.2–689.5)∗∗ |
| IgE (IU/mL) | 722.9 (573.0–912.1) | 443.9 (159.1–1238.2) | 726.1 (352.4–1495.9) | 1463.7 (805.9–2658.4)∗ |
| IL-2 (pg/mL) | 26.1 (21.0–32.4) | 34.7 (19.7–61.2) | 24.1 (16.0–36.3) | 21.3 (14.4–31.6) |
| IL-4 (pg/mL) | 1.2 (0.8–1.7) | 0.7 (0.1–5.4) | 0.9 (0.1–5.0) | 0.8 (0.2–2.4) |
| IL-5 (pg/mL) | 10.9 (4.6–25.8) | 17.1 (4.4–66.6) | 11.8 (9.4–14.9) | 5.1 (1.2–21.7) |
| IL-6 (pg/mL) | 13.7 (11.2–16.8) | 16.1 (7.9–32.8) | 10.8 (5.9–19.7) | 9.8 (6.4–14.8) |
| IL-8 (pg/mL) | 107.2 (91.8–125.2) | 105.8 (65.5–170.9) | 91.8 (61.1–138.1) | 99.3 (71.1–138.7) |
| IL-10 (pg/mL) | 8.5 (7.1–10.1) | 15.3 (6.8–34.6)∗ | 7.1 (4.8–10.5) | 6.6 (4.9–8.8) |
| IL-12p70 (pg/mL) | 9.5 (7.5–12.1) | 15.3 (5.7–41.1) | 7.4 (5.2–10.5) | 6.3 (4.1–9.8) |
| IL-13 (pg/mL) | 1.2 (0.9–1.5) | 4.7 (1.5–15.0)∗∗ | 1.3 (0.6–2.7) | 1.9 (0.9–3.9) |
| IFN-γ (pg/mL) | 131.5 (98.4–175.8) | 162.9 (49.7–533.2) | 70.1 (35.6–138.0)∗ | 95.5 (38.7–235.7) |
| GM-CSF (pg/mL) | 55.1 (43.9–69.0) | 72.8 (38.8–136.5) | 45.5 (22.1–93.4) | 45.0 (23.0–87.9) |
| TNF-α (pg/mL) | 8.2 (6.7–10.2) | 10.4 (3.7–28.9) | 9.1 (5.1–16.0) | 6.4 (3.8–10.7) |
STH: soil-transmitted helminth.
aOne child did not agree on providing blood sample.
∗ p < 0.05.
∗∗ p < 0.01.