Table 5.
Univariate analysis of the impact of CAF-related proteins in the stromal component of phyllodes tumor on patient prognosis using the log-rank test.
| Parameters | Number of patients Total/recurrence/metastasis | Disease-free survival | Overall survival | ||
|---|---|---|---|---|---|
| Median survival (95% CI) months | p value | Median survival (95% CI) months | p value | ||
| Podoplanin | 0.936 | 0.494 | |||
| Negative | 52/5/3 | 160 (146–174) | 166 (155–178) | ||
| Positive | 144/13/5 | 166 (158–175) | 177 (171–182) | ||
| Prolyl 4-hydroxylase | n/a | n/a | |||
| Negative | 192/18/8 | n/a | n/a | ||
| Positive | 4/0/0 | n/a | n/a | ||
| FAPα | 0.099 | 0.233 | |||
| Negative | 188/16/7 | 164 (157–171) | 172 (167–177) | ||
| Positive | 8/2/1 | 131 (71–191) | 162 (123–200) | ||
| S100A4 | 0.607 | 0.792 | |||
| Negative | 65/5/3 | 163 (152–174) | 168 (159–177) | ||
| Positive | 131/13/5 | 165 (155–174) | 176 (170–182) | ||
| PDGFRα | 0.698 | 0.002 | |||
| Negative | 179/16/5 | 167 (159–174) | 177 (173–182) | ||
| Positive | 17/2/3 | 121 (102–140) | 113 (90–136) | ||
| PDGFRβ | 0.394 | 0.087 | |||
| Negative | 80/6/1 | 164 (154–174) | 174 (170–178) | ||
| Positive | 116/12/7 | 163 (153–173) | 172 (164–179) | ||
| NG2 | 0.830 | 0.216 | |||
| Negative | 93/8/2 | 145 (136–154) | 155 (151–160) | ||
| Positive | 103/10/6 | 165 (155–175) | 172 (164–180) | ||