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. 2016 Nov 1;2016:4218989. doi: 10.1155/2016/4218989

Table 6.

Multivariate analysis of disease-free and overall survival in patients with phyllodes tumors.

Included factor Disease-free survival Overall survival
Hazard ratio 95% CI p value Hazard ratio 95% CI p value
Histologic grade 0.002 N/A
 Benign versus borderline/malignant 7.990 2.196–29.07 N/A N/A
Stromal cellularity 0.597 0.467
 Mild versus moderate/marked 0.625 0.109–3.569 2.862 0.169–48.60
Stromal atypia 0.886 0.708
 Mild versus moderate/marked 0.881 0.158–4.925 0.630 0.056–7.049
Stromal mitosis 0.854 0.437
 0–4/10 HPF versus >4/10 HPF 0.782 0.057–10.81 0.210 0.004–10.70
Stromal overgrowth 0.029 0.006
 Absent versus present 7.288 1.225–43.35 58.10 3.116–1083
Tumor margin 0.275 0.187
 Circumscribed versus infiltrative 0.468 0.120–1.830 0.321 0.060–1.732
PDGFRα (stromal) 0.867 0.050
 Negative versus positive 0.879 0.193–4.008 5.486 1.003–30.01

HPF, high-power field.