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. 2016 Nov 15;7:521. doi: 10.3389/fphys.2016.00521

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Copyright © 2016 Yao, Jiang, Li, Jiang, Franlin, Lancaster, Huang and Yue.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Brain regions showing strengthened functional connectivity during concentric contractions compared to eccentric contractions (CC-EC). Axial slices of brain clusters showing higher functional connectivity (uncorrected p < 0.01) during concentric than eccentric muscle contractions. The color bar indicates the raw T-value from the paired sample T-test. A wide spread regions including the left supplementary motor cortex (SMA) and cerebellum were found to have strengthened connectivity with the seed region (left M1).