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. 2016 Nov 15;6:36819. doi: 10.1038/srep36819

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The graph of normalized effective number of genes (π′_jk) for every pair versus their effective length (L′_jk) for all is shown as a circle (open circle). Panel (a) represents the preferential CT location data from fibroblast nuclei and (b) represents lymphocyte data. The coordinates representing pairs, wherein both CTs are from nuclear interior (triangle), periphery (box), and spatially intermediate (star) regions, are superimposed over those representing all pairs (open circle). The ones shown in the open circle that do not overlap with either a triangle, box, or star, represent those pairs where CTs belong to a different mix of spatial categories. Only unambiguous spatial CT positions from Table S1 are represented.

Inline graphic — The graph of normalized effective number of genes (π′_jk) for every pair versus their effective length (L′_jk) for all is shown as a circle (open circle). Panel (a) represents the preferential CT location data from fibroblast nuclei and (b) represents lymphocyte data. The coordinates representing pairs, wherein both CTs are from nuclear interior (triangle), periphery (box), and spatially intermediate (star) regions, are superimposed over those representing all pairs (open circle). The ones shown in the open circle that do not overlap with either a triangle, box, or star, represent those pairs where CTs belong to a different mix of spatial categories. Only unambiguous spatial CT positions from Table S1 are represented.