Table 1.
Patient Characteristics
| Characteristic | n/Na (%) | Characteristic | n/Na (%) |
|---|---|---|---|
| Age, yr., meanb(SD) | 43.1 (11.57) | Neurological symptoms | |
| Sex, male | 486/1088 (45) | Headache | 271/860 (32) |
| Ethnicity | Sensory abnormalities | 138/484 (29) | |
| Caucasian | 461/739 (62) | Hypaesthesia | 39/174 (22) |
| African | 218/739 (29) | Paraesthesia | 69/334 (21) |
| Other | 27/739 (4) | Neuropathic pain | 25/216 (12) |
| Unknown | 33/739 (4) | Gait abnormalities | 128/466 (28) |
| Presentation of disease | Visual impairment | 105/450 (23) | |
| History of sarcoidosis | 229/728 (31) | Fatigue | 47/202 (23) |
| Systemic sarcoidosis at admission | 256/440 (58) | Motor abnormalities | 103/552 (19) |
| Primary neurological presentation | 344/662 (52) | Hemiparesis | 41/454 (9) |
| Isolated neurosarcoidosis | 169/770 (22) | Paraparesis | 37/348 (11) |
| Systemic involvement | Ataxia | 64/387 (17) | |
| Pulmonary | 316/469 (67) | Vertigo | 39/277 (14) |
| Eye | 117/469 (25) | Hearing impairment | 97/716 (14) |
| Dermatological | 99/469 (21) | Seizures | 132/965 (14) |
| Rheumatological | 99/469 (21) | Nausea | 11/84 (13) |
| Otorhinolaryngeal | 43/469 (9) | Diplopia | 41/361 (11) |
| Hepatic | 37/469 (8) | Micturition abnormalities | 23/206 (11) |
| Cardial | 26/469 (6) | Dysarthria | 36/413 (9) |
| Constitutional symptoms | 106/469 (23) | Dysphagia | 44/481 (9) |
| Cranial nerve palsy | 572/1047 (55) | Psychiatric symptoms | 30/390 (8) |
| n. VII palsy | 227/937 (24) | Nystagmus | 11/172 (6) |
| n. II palsy | 190/910 (21) | Papilledema | 23/354 (6) |
| n. V palsy | 111/942 (12) | Site of neurological involvement | |
| n. VIII palsy | 102/914 (11) | Spinal cord disease | 98/543 (18) |
| n. VI palsy | 63/906 (7) | Peripheral neuropathy | 97/558 (17) |
| n. III palsy | 46/869 (5) | Polyneuropathy | 56/487 (11) |
| n. IX–X palsy | 32/882 (4) | (Multiple Mononeuropathies) | 16/137 (12) |
| n. I palsy | 17/889 (2) | Radiculopathy | 7/140 (5) |
| n. IV palsy | 17/869 (2) | Meningitis | 105/648 (16) |
| n. XI palsy | 5/882 (1) | Myopathy | 43/288 (15) |
| n. XII palsy | 12/882 (1) | Neuro-endocrinec | 90/1034 (9) |
| >1 cranial nerve involved | 206/724 (28) | Hydrocephalus | 52/570 (9) |
a n/N: number for which a certain characteristic is present out of the total number of patients for which it was described
b The mean age was recalculated from averages presented in 27 studies (967 patients)
c Panhypopituirism (n = 34), Diabetes insipidus (n = 21), amenorrhea (n = 5), hypothermia/hypotension (n = 1), galactorrhoea (n = 1), not further specified (n = 28)