Table 3.
Relationships between serum CA 19-9 and clinicopathological factors in clinical stage I lung adenocarcinoma patients
| Patient characteristics | CA 19-9 positive n (%) (n = 54) | CA 19-9 negative n (%) (n = 62) | P |
|---|---|---|---|
| Age (years) | |||
| SD | 9.1 | 8.3 | 0.028 |
| Mean | 69.2 | 65.6 | |
| Sex | |||
| Male | 29 (54) | 30 (48) | 0.582 |
| Female | 25 (46) | 32 (52) | |
| Smoking status | |||
| Never | 30 (56) | 32 (52) | 0.712 |
| Current or former | 24 (44) | 30 (48) | |
| Vessel invasion | |||
| Absent | 39 (72) | 55 (89) | 0.032 |
| Present | 15 (28) | 7 (11) | |
| Pleural invasion | |||
| Absent | 41 (76) | 57 (92) | 0.023 |
| Present | 13 (24) | 5 (8) | |
| p-N status | |||
| No metastasis | 47 (87) | 59 (95) | 0.184 |
| Metastasis | 7 (13) | 3 (5) | |
| Cancer invasive factor | |||
| Negative | 29 (54) | 49 (79) | 0.005 |
| Positive | 25 (46) | 13 (21) | |
| c-Stagea | |||
| IA | 44 (81) | 50 (81) | 1.000 |
| IB | 10 (19) | 12 (19) | |
| p-Stageb | |||
| I | 45 (83) | 59 (95) | 0.063 |
| II/III | 9 (17) | 3 (5) | |
| PAS stain | |||
| Negative | 32 (59) | 54 (87) | 0.001 |
| Positive | 22 (41) | 8 (13) | |
CA 19-9 carbohydrate antigen 19-9, PAS periodic acid-Schiff stain, SD standard deviation
a Clinical stage; b Pathological stage