Table 5.
Enriched or depleted features in significantly regulated TFs
| Class | Up | Down | ||||
|---|---|---|---|---|---|---|
| Term | Obs/Exp | P(Benj) | Term | Obs/Exp | P(Benj) | |
| Pioneers | Ets | 9/0 | 2.2e-07 | |||
| zf-H2C2_2 | 25/9 | 1.2e-05 | zf-H2C2_2 | 69/18 | 1.0e-08 | |
| KRAB | 36/10 | 1.1e-08 | ||||
| zf-H2C2_4 | 14/3 | 9.2e-05 | ||||
| Settlers | HLH | 20/1 | 2.5e-09 | HLH | 18/2 | 3.9e-09 |
| Ubiquitination | 33/18 | 4.7e-04 | ||||
| Sumoylation | 11/5 | 4.6e-02 | ||||
| PPI | 5/11 | 4.9e-02 | ||||
| Migrants+ | PPI | 20/11 | 6.1e-03 | |||
| Hormone_recep | 19/1 | 6.6e-09 | ||||
| zf-C2H2 | 33/8 | 7.3e-09 | ||||
| zf-C4 | 19/1 | 9.7e-09 | ||||
| Migrants- | HMG_box | 11/1 | 1.1e-05 | |||
| zf-H2C2_2 | 1/14 | 3.6e-04 | ||||
| Homeobox | 17/5 | 9.3e-04 | ||||
| Methylation | 16/8 | 4.2e-02 | ||||
| All | Ubiquitination | 74/49 | 5.4e-05 | Ubiquitination | 112/90 | 8.4e-03 |
| bZIP_1 | 12/2 | 1.8e-04 | ||||
| HLH | 20/6 | 2.7e-04 | ||||
| Ets | 10/2 | 1.1e-03 | ||||
| Sumoylation | 27/15 | 5.1e-03 | ||||
| PPI | 50/37 | 1.8e-02 | ||||
| Phosphorylation | 144/136 | 4.9e-02 | Phosphorylation | 269/252 | 7.7e-04 | |
| zf-H2C2_2 | 113/63 | 5.7e-08 | ||||
| zf-C2H2 | 56/29 | 6.0e-05 | ||||
| zf-C4 | 20/6 | 4.8e-05 | ||||
| Hormone_recep | 20/6 | 8.4e-05 | ||||
| KRAB | 58/34 | 8.9e-04 | ||||
| zf-C2H2_4 | 24/10 | 2.5e-03 |
Only features with at least 9 occurrences (as observed for enrichments or expected for depletions) are listed. Depleted features are highlighted in italics. The All category shows enrichment analysis of all significantly up- or down-regulated genes, independent of functional classification