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. 2016 Nov 14;7:57. doi: 10.1186/s13293-016-0110-x

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Body weight, organ weights, and albuminuria in male (blue bars) and female (red bars) mice at 3, 5, 14, and 18 months of age. a Body weight (BW), b heart weight, c heart weight to BW ratio, d total kidney weight, e total kidney weight to BW ratio, and f albuminuria. Data were analyzed using a 2-way ANOVA with the factors sex, age and their interaction. Tukey post hoc tests were performed where appropriate. *P < 0.05, **P < 0.01, ****P < 0.0001 as compared to age-matched male. ^# P < 0.05, ^## P < 0.01, ^### P < 0.001, ^#### P < 0.0001 as compared to the 3-month-old counterpart. ^† P < 0.05, ^†† P < 0.01, ^††† P < 0.001, ^†††† P < 0.001 as compared to the 5-month-old counterpart. ^§P < 0.05, ^§§P < 0.01, ^§§§§P < 0.0001 as compared to the 14-month-old counterpart