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. 2016 Nov 15;17:226. doi: 10.1186/s13059-016-1087-9

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Nitrogen availability influences gene sequences. a The average mRNA nitrogen content per codon for 3003 orthologous genes in the Kinetoplastida. b The average nitrogen content per double stranded codon (dsDNA) for the same genes. c As in a but for 168 orthologous Mollicute genes. d As in b but for the Mollicutes. The y-axis is the probability density function (PDF) for the distributions