Fig. 6.
Selection-mutation model of codon use can predict the metabolic capacity of parasites from raw nucleotide sequences. LN (green), MN (yellow) and HN (orange) are species with low, medium and high nitrogen availability, respectively. Species denoted with an asterisk (grey) are the new species, each of which is predicted to be a HN parasite. The presence of named genes involved in arginine catabolism and amino sugar catabolism is indicated by orange boxes. Gene names are provided below the boxes and the abbreviations correspond to the following genes: tr. transporter, arcA arginine deiminase, argF ornithine carbamoyltransferase, arcC carbamate kinase, nanA N-acetylneuraminate lyase, nanK/nagC N-acetylmannosamine kinase, nanE N-acetylmannosamine-6-p epimerase, nagA N-acetyl-D-glucosamine-6-phosphate amidohydrolase, nagB D-glucosamine-6-phosphate aminohydrolase, HyL hylauronate lyase, ugl glucuronidase. Grey outlined boxes encode aguA, whose protein product catalyses the same reaction as the product of arcA on an equivalent substrate