Table 2.

Examples of alerts designed to detect drug-related events

Ref.	Alert designed for detection
Stockwell et al[37]	Abnormal laboratory value exceeding recommended upper limit Examples
Harinstein et al[38]	ACE inhibitor/ARB and patient’s serum potassium is > 6 mmol/L INR > 4 and on warfarin Blood glucose < 40 mg/dL and on antidiabetic agent Platelet count < 50000/mm3 and on a drug that causes thrombocytopenia
Kane-Gill et al[39]	Unexpected discontinuation of drug
Kane-Gill et al[17,39]	Antidote evaluations such as flumazenil, naloxone, sodium polystyrene, protamine, dextrose 50%; lepirudin use; argatroban use

ACE: Angiotensin converting enzyme; ARB: Angiotensin II receptor blocker; INR: International normalized ratio.