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. Author manuscript; available in PMC: 2017 Nov 11.
Published in final edited form as: Vaccine. 2016 Oct 13;34(47):5768–5776. doi: 10.1016/j.vaccine.2016.09.063

Figure 1.

Figure 1

Oral administration of Lip-LcrV L. plantarum is not protective. a, 50% maximum binding titers were calculated for total LcrV specific Ig levels in mice vaccinated and boosted with Lip-LcrV L. plantarum(n=10), L. plantarum transfected with plasmid lacking LcrV (empty vector) (n=10), or IM with rLcrV in alum(n=5). b, survival of mice orally vaccinated and boosted with Lip-LcrV L. plantarum, empty vector or vaccinated and boosted IM with rLcrV in alum after challenge with 10× LD50 or 100× LD50 of Y. pestis CO92pgm−. These data are representative of two experiments. *-p<0.01 rLcrV IM 10 or 100 LD50 vs all other groups.