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. 2016 Jul 21;100(6):1395–1404. doi: 10.1189/jlb.3A0316-125R

Figure 5. Dexamethasone suppresses IL-33-induced enhancement of IgE-mediated responses.

Figure 5.

(A) After IgE sensitization, BMMCs were activated with IL-33 (50 ng/ml) alone, 50 ng/ml of antigen alone (XL), or both together, and simultaneously treated with vehicle or Dex (1 µM). Supernatants collected 6 h after activation were analyzed by ELISA. Data are representative of 3 independent experiments performed in triplicate. (B) BMMCs treated as in (A) were assessed for migration. Fold migration was normalized to that of medium alone. Data are representative of 3 independent experiments performed in triplicate. Tukey’s multiple-comparisons test was performed to calculate the P-values. **P < 0.01; ***P < 0.001; ****P < 0.0001.