Figure 7. Dex suppresses IL-33 induced cytokine production from human skin MCs.

After IgE sensitization, human skin MCs from 4 healthy donors were activated with IL-33 (100 ng/ml), antigen (50 ng/ml), or both together and simultaneously treated with vehicle or Dex (1 µM). (A) Supernatants collected 16 h after activation were analyzed by ELISA. Data are ± sd of 6 replicates per sample. P-values indicate differences between relevant pairs of samples ± dexamethasone. *P < 0.0001, ^#P < 0.001.