Table 2.
Adjusted risk ratios for different outcomes by diagnostic group.
| Diagnostic groupd | Na (ne) | All-cause mortalitya (N = 573) |
Na (ne) | Institutionalizationa,b (N = 545) |
Na (ne) | Dead or dependent at 3 years and independent at baselinea,c (N = 393) |
|||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | OR | 95% CI | ||||
| Control | 255 (54) | 1.00 | – | 253 (11) | 1.00 | – | 202 (35) | 1.00 | – |
| Parkinson's disease | 198 (72) | 2.49 | (1.72, 3.58) ∗ | 195 (26) | 3.98 | (1.98, 8.00) ∗ | 147 (50) | 3.87 | (2.18, 6.86) ∗ |
| Atypical parkinsonismd |
120 (92) |
6.85 |
(4.78, 9.81) ∗ |
97 (42) |
14.2 |
(7.17, 28.2) ∗ |
44 (39) |
45.3 |
(15.3, 134.5)∗ |
| Vascular Parkinsonism | 37 (27) | 6.32 | (3.91, 10.2)∗ | 32 (8) | 6.72 | (2.47, 18.2)∗ | 13 (11) | 24.6 | (4.90, 123.4)∗ |
| Dementia with Lewy bodies | 41 (33) | 7.75 | (4.88, 12.3)∗ | 33 (22) | 27.7 | (13.3, 57.6)∗ | 13 (12) | 73.1 | (8.80, 606.7)∗ |
| Parkinson Plus | 42 (32) | 6.58 | (4.13.10.5) ∗ | 32 (12) | 11.4 | (4.70, 27.7) ∗ | 18 (16) | 55.2 | (9.80, 311.5) ∗ |
N = total number of patients and controls included in analysis. Na = number of people included in analysis; Ne = number of events; HR hazards ratio; OR odds ratio.
* p-value <0.001.
a
Analysis adjusted for: age, sex, living alone, vascular co-morbidity, smoking, deprivation category.
b
Analysis with competing risk for death on those not institutionalized at baseline.
c
Analysis only includes those independent at baseline, N = 393 due to missing baseline Schwab & England scores.
d
Atypical parkinsonian patients analysed all together and repeated below subdivided into separate diagnostic groups.