Table 1. SCI alters the inflammatory cell phenotype in GALT.
| MLNs | B cells (B220+) | T cells (CD4+) | T cells (CD8+) | Macrophages (CD11b+) | DCs (CD11c+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cells | MFI | Cells | MFI | Cells | MFI | Cells | MFI | Cells | MFI | |||||
| % | % | % | % | % | ||||||||||
| Naive | 26.23 | 1,486 | 58.20 | 6,287 | 18.33 | 5,619 | 1.42 | 499 | 3.43 | 167 | ||||
| 3 dpi | 53.83a | 1,355 | 41.03a | 5,943 | 34.65a | 10,801 | 2.58a | 501 | 3.7 | 413.8a | ||||
| 7 dpi | 40.45 | 1,859 | 37.88a | 6,117 | 34.98a | 7,016 | 2.15a | 461 | 4.65 | 216 | ||||
| 28 dpi | 43.38 | 2,181a | 38.48a | 6,505 | 32.28a | 9,237 | 2.04a | 471 | 4.73 | 339.5a | ||||
| PPs | ||||||||||||||
| Naive | 86.38 | 1,219 | 14.525 | 4,398 | 5.57 | 1,038 | 0.74 | 336 | 2.83 | 151.0 | ||||
| 3 dpi | 74.33 | 1,692a | 21.23 | 4,721 | 14.95a | 5,048 | 0.71 | 348 | 3.91a | 214.5a | ||||
| 7 dpi | 85.88 | 1,692a | 13.65 | 3,998 | 9.60 | 4,386 | 0.32 | 308 | 2.87 | 199.8a | ||||
| 28 dpi | 87.43 | 1,992a | 13.48 | 3,556 | 9.04 | 3,238 | 0.24 | 362 | 2.90 | 192.8a | ||||
The number (percent cells) and expression level of several immune cell phenotypic markers were altered after SCI. MFI, mean fluorescent intensity.
P < 0.05, ANOVA.