Figure 4.

PC-3 in vitro cell uptake assay. PC-3 cells (1 × 105 per well in 24-well plates) were incubated at 37 °C for 1, 2, or 4 h with purified 8a (1 μCi) alone (blue diamonds) or with 2 μg AE105 (red squares) to block uPAR-mediated binding. Data represent the amount of activity associated with the cells as a percentage of the total activity applied ± standard deviation of quadruplicate wells.