Table 2.
Radiochemical Purities of 6a via the postlabeling Pathway from Ligand 4a
ligand concentration | 6a
|
|
---|---|---|
30 min | 60 min | |
1 × 10−4 M | 96% | – |
5 × 10−5 M | 87% | 91% |
Reactions were heated at 70 °C in 10 mM sodium phosphate pH 7.4 buffer for the times indicated and then allowed to cool briefly before aliquots were removed for analysis by radio-HPLC using HPLC method 1 or 2.