Table 4. P-glycoprotein substrate drugs.

Therapeutic class	Examples
Antimicrobial agents	Erythromycin
	Grepafloxacin
Anticancer agents	Doxorubicin*
	Vincristine*
Immunosuppressants	Cyclosporin A
	Tacrolimus
Steroids	Dexamethasone
	Hydrocortisone
Gastrointestinal drugs	Loperamide*
	Domperidon
Cardiac drugs	Quinidine
	Digoxin

^*Previously documented interactions with canine mdr1-1 Δ (16, 17). Information collected from refs. 45-47. Reviewed in ref. 48.