FIG 2.

Effectiveness of 81.39a treatment in ferrets. Viral titers in nasal washes (NW) (A), nasal turbinates (NT) (B), trachea (TR) (C), and bronchoalveolar lavage fluid (BALF) (D), as well as inflammatory cell counts (E) and protein concentrations (F) in BALF. Groups of four ferrets were inoculated with 10⁶ TCID₅₀ of H1N1pdm virus and treated with 25 mg/kg of control IgG or 81.39a at the indicated hours postinoculation. Nasal washes were collected 1 to 5 dpi, while respiratory tract tissues and BALF were harvested at 5 dpi. All data are expressed as the means ± SD. In panels B to D, each data point represents the viral titer of an individual animal. Dotted lines in lung viral titers indicate the limit of detection (<1.6 log₁₀). *, P < 0.05.