FIG 6.
Gene validation. (A to H) TaqMan assays were done on FILIP1, upregulated at 10, 14, and 100 dpi (A); GFAP, downregulated at 3, 7, 10, 14, and 100 dpi (B); CPLX1, downregulated at 3, 7, 10, 14, and 100 dpi (C); MXA, upregulated at 3 and 7 dpi (D); BST2, upregulated at 3 and 7 dpi (E); SYNPR, upregulated at 7 dpi (F); SEC62, upregulated at 10 dpi (G); and APLP1, downregulated at 10, 14, and 100 dpi (H) (one additional ganglion tissue from the same animal was used at 7 dpi and 10 dpi). *, P < 0.05 compared to day 0. (I) Heat map of genes confirmed by TaqMan in panels A to H showing the median normalized transcript number for each day postinfection.