TABLE 1.

Statistical analysis of data in Fig. 5

Prion seed and substrate	Fig. no.	Dilution	Pa
BSE
FL bovine	5A	10−3	<0.05
		10−4	<0.05
		10−5	<0.05
		10−6	<0.05
FL WTD		10−3	<0.05
		10−4	<0.05
		10−5	NS
		10−6	NS
Truncated bovine	5B	10−3	<0.05
		10−4	<0.05
		10−5	<0.05
		10−6	NS
Truncated WTD		10−3	<0.05
		10−4	<0.05
		10−5	NS
		10−6	<0.05
CWD
FL WTD	5C	10−3	<0.05
		10−4	<0.05
		10−5	<0.05
		10−6	NS
FL bovine		10−3	<0.05
		10−4	<0.05
		10−5	<0.05
		10−6	NS
Truncated WTD	5D	10−3	<0.05
		10−4	<0.05
		10−5	<0.05
		10−6	NS
Truncated bovine		10−3	NS
		10−4	NS
		10−5	NS
		10−6	NS
sCJD
FL human	5E	10−3	<0.05
		10−4	<0.05
		10−5	<0.05
		10−6	<0.05
FL bovine		10−3	<0.05
		10−4	<0.05
		10−5	<0.05
		10−6	<0.05
Truncated human	5F	10−3	<0.05
		10−4	<0.05
		10−5	<0.05
		10−6	<0.05
Truncated bovine		10−3	<0.05
		10−4	NS
		10−5	NS
		10−6	NS

^aDifference from the unseeded control value. NS, not significant.