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Back-passage of tg650-derived L-BSE prions into bovine PrP mice
| Inoculum | Passage no. | Incubation time (days [mean ± SEM]) |
|---|---|---|
| tg650-L-type | 1 | 233 ± 14 (6/6)a |
| 2 | 210 ± 5 (6/6) | |
| 3 | 214 ± 2 (6/6) | |
| Bovine L-type | 1 | 245 ± 15 (8/8) |
Values in parentheses represent the number of mice with neurological disease and positive for PrPres in the brain by immunoblotting/number of inoculated tg110 mice.
