TABLE 2.

Breadth and the potency of GPI-anchored antibody derivatives (scFv, HCDR3, and VHH) and soluble IgG or scFv and sdAb of various human monoclonal antibodies^a

^aNeutralization breadth is presented as the number of HIV-1 strains neutralized per number of HIV-1 strains tested. Colors represent the neutralization potency. For GPI-anchored antibody derivatives, red stands for an average inhibition of ≥98%, green an average inhibition between 50 and 80%, and gray an average inhibition between 0 and 50%. For soluble IgG, scFv, or VHH, red stands for a median 50% inhibitory concentration (IC₅₀) of <1 μg/ml, yellow an IC₅₀ between 1 and 10 μg/ml, green an IC₅₀ between >10 and 50 μg/ml, and gray an IC₅₀ of >50 μg/ml or no neutralization. ND, not done.