Figure 3.

Quantitative assessment of GFAP (A), VEGF (B), TSP1 (C), and PEDF (D) expression in mouse eyes receiving different amounts of propranolol. The expression of desired genes was determined by qPCR and specific set of primers as detailed in the Methods. Please note a dramatic increase in the level of GFAP in retinas with 0.6 μg propranolol. The VEGF levels (all isoforms) were not affected at 0.3 μg propranolol, but a modest increase was detected in retinas with 0.15 μg propranolol. The level of TSP1 was increased at 0.3 μg propranolol but PEDF levels did not change.