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. Author manuscript; available in PMC: 2018 Jan 1.

Published in final edited form as: Acta Biomater. 2016 Sep 30;47:71–80. doi: 10.1016/j.actbio.2016.09.045

(A) Body weight variations mice from different treatment of A549 WT and A549 DDP tumor bearing mice. (B) Histograms that show the levels of several safety parameters in the different treatment groups. The parameters tested were: the concentrations of the enzymes aspartate transaminase (AST) and alanine transaminase (ALT) that are reasonably sensitive indicators of liver damage; the number of white blood cells (WBC); the number of platelets; serum creatinine and blood urea nitrogen as indicators of kidney function.

(A) Body weight variations mice from different treatment of A549 WT and A549 DDP tumor bearing mice. (B) Histograms that show the levels of several safety parameters in the different treatment groups. The parameters tested were: the concentrations of the enzymes aspartate transaminase (AST) and alanine transaminase (ALT) that are reasonably sensitive indicators of liver damage; the number of white blood cells (WBC); the number of platelets; serum creatinine and blood urea nitrogen as indicators of kidney function.