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. 2016 Nov 14;18(12):724–731. doi: 10.1016/j.neo.2016.10.002

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Impact of HMGA1 on cell transformation in in vitro models. Effect of overexpression of HMGA1 in (A) PCL5 and (B) HEPG2 and down-regulation of HMGA1 in (C) SNU449 and (D) SNU182 on anchorage-independent growth. Quantification was performed by defining the number and size of colonies. All experiments were performed in triplicates. Error bars, SD of the mean. Statistical comparisons were performed using unpaired t-tests with Welch correction. P < .05 was considered statistically significant.