Table 2. MICs of Zantrins, μM.
| Organism | Z1 | Z2 | Z3 | Z4 | Z5 |
|---|---|---|---|---|---|
| E. coli MC 1000 | 20 | 40 | >80 | >80 | >80 |
| E. coli DRC 39 (ΔacrAB::Tn903kanr)* | 20 | 5 | 10 | >80 | 80‡ |
| E. coli DRC 40 (ΔacrAB::Tn903kanr ftsZ84-ts)* | 40 | 5 | 10 | >80 | 80§ |
| E. coli DRC 42 (ΔacrAB::Tn903kanr recA::cat)* | 20 | 5 | 5 | >80 | 80‡ |
| S. dysenteriae 60R | 10 | 10 | 20 | >80 | >80 |
| V. cholerae N16961 | 5 | 5 | 5 | >80 | >80 |
| P. aeruginosa PAK | 40 | >80 | >80 | >80 | >80 |
| P. aeruginosa (ΔmexAB)* | 40 | >80 | >80 | >80 | >80 |
| B. subtilis JH 642 | 1.25 | 2.5 | 2.5 | 2.5 | 40 |
| B. cereus CIP 3852 | 0.625 | 5 | 20 | 2.5 | 80 |
| S. aureus H | 2.5 | 1.25 | 5 | 10 | >80 |
| S. aureus MRSA† | 2.5 | 2.5 | 10 | 10 | >80 |
| S. pneumoniae TIGR 4 | 0.312 | 2.5 | 5 | 10 | >80 |
| C. perfringens Strain 13 | 5 | 10 | 80 | 5 | >80 |
*
DRC 39, DRC 40, and DRC 42 are derivatives of the wild-type E. coli strain MC 1000; ΔmexAB mutant of P. aeruginosa is a derivative of the wild-type strain PAK.
†
Methicillin-resistant S. aureus is a clinical isolate from Tufts—New England Medical Center.
‡
Denotes residual turbidity due to unlyzed filaments, filament ghosts, and some short nonmotile cells.
§
Faint turbidity, less than in DRC 39; very long filaments, some with increased diameter, filament ghosts, and few short cells.