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. 2004 Jul 27;101(32):11839–11844. doi: 10.1073/pnas.0404474101

Fig. 6.

Fig. 6.

Marker profile of human cells depends on proximity to the lesion. (A) Immunostaining of human cells (brown) with human-specific antibody SC121. Boxes show the location of the cells in the other panels. (Scale bar = 500 μm.) (BF) Confocal images: human cells labeled with SC121 are green, nuclei stained with Hoechst are blue, and various phenotypic markers are in red. An asterisk denotes double-labeled cells. (Scale bar = 20 μM.) (B) Many human cells at the lesion border (box 1 in A) express β-tubulin III. (C) Higher magnification of demarked area in B.(D) Orthogonal view to confirm double labeling with the human marker and β-tubulin III. (E) Cells at the lesion border also express GFAP. (F) The migrating cells (box 2 in A) express doublecortin.