Table 2.
Drug effects on blood pressure and renal function markers.
| Group 1 (n = 12) | Group 2 (n = 12) | |||||
|---|---|---|---|---|---|---|
| Baseline |
Telmisartan/ramipril
40/5 mg/day |
p value | Baseline |
Telmisartan
80 mg/day |
p value | |
| Mean ± SD or median (IQR) |
Mean ± SD or median (IQR) |
Mean ± SD or median (IQR) |
Mean ± SD or median (IQR) |
|||
| Systolic BP, mmHg | 132 ± 13 | 122 ± 10 | 0.04 | 133 ± 14 | 123 ± 15 | 0.11 |
| Diastolic BP, mmHg | 82 ± 8 | 75 ± 5 | 0.02 | 77 ± 9 | 76 ± 10 | 0.80 |
| Creatinine, mg/dL | 1.6 (1.0–2.3) | 1.5 (1.1–2.2) | 0.57 | 1.7 (1.3–2.0) | 1.5 (1.3–2.0) | 0.85 |
| GFR, mL/min per 1.73 m2 | 48 (22–71) | 47 (23–61) | 0.79 | 48 (34–66) | 55 (36–71) | 0.79 |
| Proteinuria, g/24 h | 0.52 (0.28–2.49) | 0.49 (0.22–1.15) | 0.07 | 1.28 (0.36–2.35) | 0.67 (0.44–1.68) | 0.08 |