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. Author manuscript; available in PMC: 2016 Nov 16.
Published in final edited form as: Biomacromolecules. 2016 Aug 23;17(9):3060–3066. doi: 10.1021/acs.biomac.6b00960

Figure 4.

Figure 4

Hydrolysis of CPT alone (○, dashed), loaded in p[(SEA)50-b-(nBA)50] (▲, blue), p[(AA)48-b-(nBA)50] (●, black), and p-[(AA)106-b-(nBA)50] (■) nanoparticles after incubation in DPBS at pH 7.4 at 37 °C with 3.5% human serum albumin. (top) Representative HPLC traces of hydrolyzed (~9.2 min) and intact (11.3 min) CPT after 18 h. (bottom) CPT hydrolysis over time. CPT concentration was 0.1 mg/mL for all samples except for a free CPT sample at 0.025 mg/mL (red dashed line).