Table 4.
Model | Atrial cells | Ventricular cells | Purkinje cells | |||
---|---|---|---|---|---|---|
Condition | CV (cm/s) control |
CV (cm/s) 30 µM E3G |
CV (cm/s) control |
CV (cm/s) 30 µM E3G |
CV (cm/s) control |
CV (cm/s) 30 µM E3G |
Nav1.5 WT | 55.07 | 50.84 | 49.91 | 45.72 | 67.68 | 37.20 |
Nav1.5 p.I141V | 57.44 | 53.93 | 53.63 | 49.11 | 72.43 | 42. 92 |
Nav1.5 p.R222Q | 60.93 | 56.23 | 51.93 | 45.56 | 62.72 | — |