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. 2016 Nov 16;6:37297. doi: 10.1038/srep37297

Figure 1. FTY720-P enhances TNF-induced PP2A phosphatase activity in A549 cells.

Figure 1

A549 cells were pretreated with 2.5 μM FTY720-P for 6 h, compared to vehicle-treated controls. Cells were treated with vehicle or TNF (4 ng/ml) and then PP2A enzymatic activity (measured as pmol free phosphate) detected at 1 h. Statistical analysis was performed using one-way ANOVA then Bonferroni’s post-test (where * denotes a significant effect of TNF compared to vehicle-treated cells, and § denotes a significant effect of FTY720-P on TNF-induced PP2A activity (P < 0.05)). Data are mean + SEM values from n = 3 independent experiments.