Table 4. Comparison of clinical characteristics of 68 hospitalized children infected by HAdV-7 and the other types.
| Characteristics | All (n = 68) | HAdV-7 (n = 14) | The other types (n = 54) | p value |
|---|---|---|---|---|
| Fever | 64 (94.1) | 14 (100) | 50 (92.6) | 0.574 |
| Duration days (range)* | 5.3 (1–23) | 8.6 (3–23) | 4.4 (1–21) | 0.039 |
| Median peak temperature (range) | 39.7 (37.5–42) | 39.6 (38.4–40.6) | 39.8 (37.5–42) | 0.555 |
| Cough | 51 (75) | 13 (92.8) | 38 (70.4) | 0.162 |
| Runny nose | 21 (30.9) | 4 (28.6) | 17 (31.5) | 1.000 |
| Sore throat | 54 (79.4) | 12 (85.7) | 42 (77.8) | 0.717 |
| Expectoration | 28 (41.2) | 8 (57.1) | 20 (37.0) | 0.173 |
| Rales | 28 (41.2) | 8 (57.1) | 20 (37.0) | 0.173 |
| Wheezing | 18 (26.5) | 6 (42.8) | 12 (22.2) | 0.173 |
| Tachypnea/dyspnea* | 26 (38.2) | 10 (71.4) | 16 (29.6) | 0.004 |
| Pleural effusion* | 10 (14.7) | 8 (57.1) | 2 (3.7) | <0.001 |
| Cyanosis | 5 (7.3) | 2 (14.3) | 3 (5.6) | 0.272 |
| Tonsillitis | 33 (48.5) | 5 (35.7) | 28 (51.8) | 0.282 |
| Extrapulmonary manifestations | ||||
| Skin rash | 8 (11.8) | 1 (7.1) | 7 (12.9) | 1.000 |
| Conjunctivitis | 4 (5.9) | 1 (7.1) | 3 (5.6) | 1.000 |
| Diarrhea* | 12 (17.6) | 6 (42.8) | 6 (11.1) | 0.012 |
| Vomiting | 9 (13.2) | 3 (21.4) | 6 (11.1) | 0.377 |
| Hepatosplenomegaly* | 21 (30.9) | 8 (57.1) | 13 (24.1) | 0.025 |
| Seizure | 8 (11.8) | 2 (14.3) | 6 (11.1) | 0.665 |
| Consciousness alteration* | 5 (7.3) | 4 (28.6) | 1 (1.8) | 0.005 |
| Clinical outcomes | ||||
| Upper respiratory tract infection | 16 (23.5) | 1 (7.1) | 15 (27.8) | 0.161 |
| Bronchitis | 7 (10.3) | 2 (14.3) | 5 (9.3) | 0.627 |
| Bronchopneumonia | 28 (41.2) | 3 (21.4) | 25 (46.3) | 0.092 |
| Pneumonia* | 17 (25) | 8 (57.1) | 9 (16.7) | 0.004 |
| Median duration of hospitalized days (range) | 10.6 (2–83) | 18.7 (3–83) | 8.5 (2–45) | 0.075 |
| Mechanical ventilation* | 7 (10.3) | 5 (35.7) | 2 (3.7) | 0.003 |
| Death* | 4 (5.9) | 4 (28.6) | 0 | 0.001 |
The values indicate the number (%) of corresponding children. “HAdV-7” group are the children infected by HAdV-7; “The other type” group are the children infected by adenovirus types 1, 2, 3, 14, 19, 21 and 55. “*”: a significant difference between groups.