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. 2016 Nov 16;6:37184. doi: 10.1038/srep37184

Figure 6. Cx43/ERK signaling is critical for clinical outcomes in traumatic HO patients.

Figure 6

(A) Normal bones (n = 15) and HO tissues (n = 20) were decalcified. Expression of Cx43 and p-ERK was detected by immunohistochemistry. (B) Quantification of Cx43 and p-ERK expression. (C) A typical radiographic three-dimensional reconstruction CT scan is shown for elbow HO with weak and strong expression of Cx43. (D) The volumes of the HO with weak and strong Cx43 expression were quantified. (t-test, *p < 0.05). (E) The overall recurrence-free survival of patients with weak and strong expression of Cx43 is shown. (F) The overall recurrence-free survival of patients with weak and strong expression of p-ERK is shown. (log-rank test).