| Anticoagulant |
Binds fibrin, antithrombin,
factor Xa, factor IXa, thrombin, heparin cofactor II and protein C
inhibitor |
| Protein Stabilizer |
Forms strong electrostatic
interactions with many heparin-binding proteins such as FGF1 and FGF2,
protecting them from deactivation |
| Anti-Inflammatory |
Binds to selectins on leukocytes
inhibiting their interaction with sialyl Lewis X (sLex),
and thus preventing interactions with endothelial cells |
| Binds and neutralizes
proteins,
enzymes, chemokines and cytokines that activate or are released from
inflammatory cells |
| Alterations in cellular
migration and/or proliferation |
Binds various growth factors
involved in cell growth and migration, such as FGFs, VEGF, and PDGF,
thus altering their ability to bind with receptors on the cell surface |
