. 2016 Oct 14;17(11):3417–3440. doi: 10.1021/acs.biomac.6b01147

Table 2. Structures and Biological Activities of Polyaromatic Anionic Heparin-Mimicking Compounds^a (Modified with Permission from Ref (81); Copyright 2002 Wiley-Liss, Inc., John Wiley and Sons).

The relative activity of each compound is presented as +, ++, +++, and ++++ representing a low (0–30%), medium (30–60%), high (60–90%), or almost complete (90–100%) inhibition of heparanase activity and SMC proliferation, or stimulated release of ECM-bound FGF2 expressed as percentage of the total ECM-bound FGF2. Note: In most cases, this polymerization will result in polymers with different structures and substitution patterns. Only one possible structure is drawn in each case.

Table 2. Structures and Biological Activities of Polyaromatic Anionic Heparin-Mimicking Compoundsa (Modified with Permission from Ref (81); Copyright 2002 Wiley-Liss, Inc., John Wiley and Sons).

Table 2. Structures and Biological Activities of Polyaromatic Anionic Heparin-Mimicking Compounds^a (Modified with Permission from Ref (81); Copyright 2002 Wiley-Liss, Inc., John Wiley and Sons).