Table 1.
Baseline patients characteristics
| Baseline characteristics | All patients (n = 73) | HTx recipients (n = 32) | Other patients (n = 41) |
|---|---|---|---|
| Age (years) | 47.6 ± 12.1 | 48.91 ± 11.24 | 40.02 ± 14.53 |
| Sex | |||
| Females | 16 | 9 | 7 |
| Males | 57 | 23 | 32 |
| BMI (kg/m2) | 24.37 ± 4.11 | 24.31 ± 3.99 | 24.05 ± 5.43 |
| NYHA Class | |||
| I, II, | 35 | 31 | 4 |
| III, IV | 39 | 1 | 38 |
| Coronary artery disease | 3 | 3 | 0 |
| Myocardial infarction | 0 | 0 | 0 |
| Hypertension | 11 | 11 | 0 |
| Diabetes mellitus | 9 | 9 | 0 |
| Prior pacemaker implantation | 2 | 2 | 0 |
| Prior cardioverter-defibrilator implantation | 0 | 0 | 0 |
| Prior cardiac resynchronisation therapy device implantation | 0 | 0 | 0 |
| Prior rheumatic disease | 1 | 1 | 0 |
| Renal failure | 14 | 9 | 5 |
| GFR (ml/min/m2) | 71.66 ± 23.48 | 53.2 ± 23.16 | 72.83 ± 12.17 |
| Blood pressure (mmHg) | |||
| Systolic | 127.58 ± 15.29 | 129.89 ± 33.3 | 99.00 ± 12.04 |
| Diastolic | 81.38 ± 11.23 | 82.95 ± 9.54 | 81.38 ± 11.23 |
| Electrocardiogram | |||
| Sinus rhytm | 70 | 30 | 42 |
| Atrioventricular block | 0 | 0 | 0 |
| Left Bundle Branch Block | 4 | 2 | 2 |
| Right Bundle Branch Block | 6 | 6 | 0 |
| Heart rate on admission (min−1) | 95.26 ± 13.48 | 95.98 ± 13.37 | 84.60 ± 12.18 |
| PQ-interval (s) | 0.147 ± 0.043 | 0.160 ± 0.06 | 0.14 ± 0.06 |
| QRS-width (s) | 0.119 ± 0.022 | 0.120 ± 0.06 | 0.18 ± 0.018 |
| QT-interval (s) | 0.36 ± 0.32 | 0.38 ± 0.14 | 0.36 ± 0.50 |
| ST-segment alterations | 5 | 2 | 3 |
| Negative T-wave | 5 | 2 | 3 |
| Cardiac Biomarkers | |||
| Creatine kinase (U/L) | 85.78 ± 82.17 | 38.26 ± 75.68 | 187.00 ± 192.85 |
| Creatine kinase- MB (U/L) | 21.44 ± 8.64 | 21.27 ± 8.86 | 16.2 ± 15.81 |
| Troponin I (ng/mL) | 0.37 ± 1.67 | 0.23 ± 0.97 | 4.51 ± 2.75 |
| Brain natriuretic peptide (pg/mL) | 312.08 ± 365.13 | 261.13 ± 284.35 | 948.02 ± 641.85 |
| Laboratory results on admission | |||
| C-reactive protein (mg/L) | 32.29 ± 8.72 | 12.21 ± 34.35 | 47.18 ± 62.20 |
| Hemoglobin concentatration (mmol/L) | 7.8 ± 1.2 | 7.61 ± 1.04 | 10.35 ± 0.67 |
| White blood cell count (1 × 109/L) | 6.47 ± 3.44 | 6.23 ± 3.19 | 10.23 ± 5.41 |
| Platelets count (1 × 109/L) | 107.78 ± 57.27 | 205.13 ± 56.97 | 215.83 ± 55.42 |
| Echocardiography | |||
| Ejection fraction (%) | 61.24 ± 14.65 | 64.32 ± 8.92 | 17.67 ± 5.16 |
| Left ventricle end diastolic diameter (mm) | 45.92 ± 14.65 | 44.41 ± 4.58 | 68.33 ± 10.04 |
| Interventricular septum (mm) | 11.9 ± 2.14 | 12.00 ± 2.07 | 9.91 ± 2.20 |
| Posterior wall (mm) | 11.38 ± 2.73 | 11.42 ± 2.73 | 10.75 ± 2.98 |
| Right ventricle end diastolic diameter (mm) | 28.19 ± 4.23 | 27.98 ± 4.13 | 32.00 ± 4.20 |
| Right ventricular systolic pressure (mmHg) | 32.39 ± 8.72 | 32.27 ± 9.00 | 33.25 ± 4.71 |
| Pericardial effusion | |||
| < 4 mm | 6 | 4 | 2 |
| > 4 mm | 0 | 0 | 0 |
| Tricuspid valve dysfunction | |||
| Mild | 5 | 5 | 2 |
| Moderate | 3 | 1 | 6 |
| Severe | 0 | 0 | 2 |
| Cardiac catheterization | |||
| Right atrial pressure (mmHg) | |||
| Systolic | 14.00 ± 7.18 | 12.00 ± 6.00 | 16.00 ± 9.00 |
| Diastolic | 8.00 ± 5.30 | 6.00 ± 3.50 | 10.00 ± 7.00 |
| Mean | 11 ± 6.14 | 8.00 ± 2.70 | 14.00 ± 8.00 |
| Right ventricular pressure (mmHg) | |||
| Systolic | 39.2 ± 17.73 | 27.00 ± 6.00 | 51.00 ± 18.4 |
| Diastolic | 7.33 ± 8.55 | 6.00 ± 4.00 | 8.00 ± 9.00 |
| End diastolic | 10 ± 6.83 | 4.00 ± 5.50 | 15.00 ± 5.00 |
| Pulmonary Artery Pressure (mmHg) | |||
| Systolic | 31.00 ± 11.64 | 24.00 ± 7.00 | 39.00 ± 11.00 |
| Diastolic | 16.33 ± 9.91 | 12.00 ± 5.00 | 20.00 ± 13.00 |
| Mean | 19.30 ± 13.70 | 15 ± 7.00 | 30.00 ± 16.50 |
Continuous variables are presented as mean ± SD. Categorical variables are presented as absolute values (n=). NYHA New York Heart Association