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. 2016 Nov 15;8:121. doi: 10.1186/s13073-016-0375-z

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — CN profiles for two breast pre-cancerous samples (P1 (a, b) and P2 (c, d)). a, c MIP arrays in the range of 40–80 ng input of DNA. b, d LC WGS from 5 ng input of DNA. Each data point in (b) and (d) represents normalized read count ratios from a 50 kb window. Segments were removed from highly repetitive or problematic regions [8]