Table 2.
The occurrence of β-lactamases and PMQR genes in ESC-R E. coli isolates.
| Isolates ID | PG | MLST | β-lactamase genes | PMQR genes | Resistance profiles | |||
|---|---|---|---|---|---|---|---|---|
| Non-ESBL | ESBL | pAmpC | Carbapenemase | |||||
| B1 | A | ST1820 | TEM-30 | qnrS, aac(6′)-Ib-cr | CFZ, CTX, CPO, ENR, DOX, GEN | |||
| H2 | A | ST746 | TEM-1 | CTX-M-14 | AMC, CFZ, CTX, CAZ, ENR, DOX, SXT | |||
| W12 | A | ST44 | TEM-1 | CTX-M-15 | AMC, CFZ, CTX, CAZ, ENR, DOX, CHL | |||
| B6 | A | ST1700 | TEM-1 | CTX-M-1, CTX-M-15, CTX-M-123 | aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, FOX, ENR, PRA, DOX, AMK, SXT | ||
| Y5 | A | ST167 | TEM-1 | SHV-12 | qnrD, qnrS | AMC, CTX, ENR, DOX, CHL, GEN | ||
| W4 | A | ST167 | TEM-1 | CTX-M-9, CTX-M-14, CTX-M-123 | OXA-48 | qnrD, qnrS | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, MEM, ENR, PRA, DOX, CHL, GEN, AMK, SXT | |
| X2 | A | ST10 | TEM-1 | CTX-M-15 | qnrD, qnrS | AMC, CFZ, CTX, CAZ, ENR, DOX, SXT | ||
| Y15 | A | ST10 | SHV-12, CTX-M-15 | qnrB, qnrD | AMC, CTX, CAZ, CPD, CPO, FOX, ENR, DOX, CHL, GEN, SXT | |||
| B3 | A | ST10 | SHV-12, CTX-M-15 | qnrB, aac(6′)-Ib-cr | AMC, CTX, CAZ, CPD, CRO, CPO, ENR, PRA, DOX, GEN, AMK, SXT | |||
| W15 | A | ST10 | TEM-1 | SHV-12, CTX-M-15 | OXA-48 | CFZ, CTX, CAZ, CPD, CRO, FOX, IPM, DOX, CHL, GEN, SXT | ||
| W6 | A | ST10 | SHV-12, CTX-M-15, CTX-M-14 | qnrB, qepA, aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CRO, CPO, FOX, ENR, PRA, DOX, CHL, SXT | |||
| Y13 | A | ST10 | TEM-1 | CTX-M-15, CTX-M-9, CTX-M-14 | qnrB, qnrD, qnrS, aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, ENR, PRA, DOX, CHL, GEN, AMK, SXT | ||
| X1 | A | ST10 | TEM-1 | CTX-M-1, CTX-M-15, CTX-M-123 | qnrS, aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, ENR, PRA, DOX, CHL, SXT | ||
| B5 | A | ST10 | TEM-1 | CTX-M-1, CTX-M-15, CTX-M-123 | qnrD, qnrS, aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, ENR, PRA, DOX, CHL, SXT | ||
| H1 | A | ST10 | TEM-1 | CTX-M-1, CTX-M-15, CTX-M-123 | CMY-2 | qnrS, aac(6′)-Ib-cr | AMC, CTX, CAZ, CRO, CPO, FOX, IPM, ENR, PRA, DOX, CHL, GEN, AMK, SXT | |
| X5 | B1 | ST75 | SHV-12, CTX-M-15 | aac(6′)-Ib-cr | AMC, CTX, CAZ, CRO, ENR, CHL, SXT | |||
| X6 | B1 | ST1177 | TEM-1 | CTX-M-15, CTX-M-123 | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, DOX, CHL, SXT | |||
| Y10 | B2 | ST375 | TEM-30 | aac(6′)-Ib-cr | AMC, CTX, CAZ, ENR | |||
| X8 | B2 | ST302 | TEM-1 | CTX-M-15 | aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, ENR, DOX, GEN | ||
| W19 | B2 | ST73 | TEM-1 | CTX-M-1, CTX-M-15, CTX-M-123 | aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, FOX, ENR, DOX, CHL | ||
| W9 | B2 | ST104 | TEM-1 | CTX-M-1, CTX-M-9, CTX-M-14 | OXA-48 | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, MEM, ENR, DOX, CHL, GEN, SXT | ||
| Y8 | B2 | ST131 | TEM-1 | CTX-M-15 | aac(6′)-Ib-cr | AMC, CTX, CAZ, CRO, ENR, PRA, DOX | ||
| X9 | B2 | ST131 | TEM-1 | CTX-M-15 | DHA-1 | qnrD, qnrS | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, MEM, ENR, PRA, DOX, CHL, SXT | |
| X16 | B2 | ST131 | TEM-1 | CTX-M-15 | OXA-48 | qnrS, qepA, aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, IPM, ENR, PRA, DOX, CHL, GEN, AMK, SXT | |
| Y11 | B2 | ST131 | TEM-1 | SHV-12, CTX-M-15 | qnrB | AMC, CFZ, CTX, ENR, DOX, SXT | ||
| Y17 | B2 | ST131 | TEM-1 | SHV-12, CTX-M-15 | aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPO, FOX, ENR, PRA, DOX, SXT | ||
| W13 | B2 | ST131 | TEM-1 | CTX-M-1, CTX-M-15 | aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, FOX, ENR, DOX, SXT | ||
| Y4 | B2 | ST131 | TEM-1 | CTX-M-15, CTX-M-123 | qnrS, aac(6′)-Ib-cr | CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, ENR, PRA, DOX, CHL, GEN, AMK, SXT | ||
| X7 | B2 | ST131 | TEM-1 | SHV-12, CTX-M-15, CTX-M-123 | CMY-2 | qnrB, qnrD, aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, ENR, PRA, DOX, CHL, GEN, AMK, SXT | |
| W11 | B2 | ST131 | TEM-1 | SHV-12, CTX-M-1, CTX-M-15, CTX-M-123 | CMY-2 | aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, ENR, PRA, DOX, CHL, GEN, AMK, SXT | |
| H6 | B2 | ST131 | TEM-1 | CTX-M-1, CTX-M-15, CTX-M-9, CTX-M-14, CTX-M-123 | aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, FOX, ENR, PRA, DOX, CHL, GEN, AMK, SXT | ||
| X12 | D | ST69 | TEM-1 | CTX-M-15, CTX-M-123 | OXA-48 | aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, MEM, ENR, PRA, DOX, CHL, GEN, AMK, SXT | |
| X15 | D | ST38 | TEM-1 | CTX-M-15, CTX-M-9, CTX-M-14 | AMC, CFZ, CTX, CAZ, CPD, CRO, DOX, CHL, SXT | |||
| X10 | D | ST405 | TEM-1 | SHV-12, CTX-M-15, CTX-M-14, CTX-M-123 | OXA-48 | aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, IPM, ENR, PRA, DOX, CHL, GEN, AMK, SXT | |
| X18 | D | ST648 | TEM-1 | SHV-12, CTX-M-15, CTX-M-9, CTX-M-14 | DHA-1 | OXA-48 | qnrB, qnrD, qnrS, qepA, aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, IPM, ENR, PRA, DOX, CHL, GEN, AMK, SXT |
| X27 | D | ST68 | TEM-30 | CTX, ENR, DOX | ||||
| Y7 | E | ST1421 | TEM-30 | qnrB, aac(6′)-Ib-cr | AMC, CFZ, CTX, CPD, ENR, PRA, DOX | |||
| W8 | E | ST2375 | SHV-12, CTX-M-15 | AMC, CFZ, CTX, CAZ, CPD, DOX, CHL, SXT | ||||
| W13 | E | ST3058 | TEM-1 | SHV-12, CTX-M-15 | OXA-48 | aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, CPO, FOX, MEM, ENR, DOX, CHL, GEN, AMK, SXT | |
| H5 | F | ST3630 | TEM-1 | CTX-M-1, CTX-M-9, CTX-M-14, CTX-M-123 | qepA, aac(6′)-Ib-cr | AMC, CFZ, CTX, CAZ, CPD, CRO, FOX, ENR, PRA, DOX, CHL, SXT | ||
AMC, amoxicillin-clavulanic acid; CFZ, cefazolin; CTX, cefotaxime; CAZ, ceftazidime; CPD, cefpodoxime; CRO, ceftriaxone; CPO, cefoperazone; FOX, cefoxitin; IPM, imipenem; MEM, meropenem; ENR, enrofloxacin; PRA, pradofloxacin; DOX, doxycycline; CHL, chloramphenicol; GEN, gentamicin; AMK, amikacin; SXT, sulfamethoxazole-trimethoprim.