Skip to main content
. 2016 Nov 15;11:131. doi: 10.1186/s13000-016-0584-1

Table 2.

Immunohistochemical profile of breast cancers containing signet ring cells

Case MUC1 MUC2 MUC4 MUC5 MUC6 ER PgR HER2 Ki67
Subcellular localization Level
1 CM Low + + 30
2 LC Low + + + 10
3 CM Low + + + 20
4 LC Low + + 10
5 LC High + 5
6 CM Low + 30
7 CM Low + + 30
8 LC Low + 5
9 LC High + + + 10
10 LC High + + + 10
11 CM Low 10
12 CM Low + 10
13 LC High + + + 10
14 CM High + + 10
15 LC High + + + 20
16 LC Low 20
17 LC High + + + 5
18 LC High + + 5
19 LC High + + 10
20 LC High + + 10
21 LC High + + 5
22 LC Low + + + 5

Abbreviations: CM cytoplasmic with circumferential accentuation pattern, LC luminal and cytoplasmic pattern