Table 1.
Characteristics of subjects
| Healthy volunteers | Acute inflammation | Whipplea | |
|---|---|---|---|
| Sex, males: females | 3:7 | 8:2 | 9:1 |
| Age (years) | 50 ± 8 | 62 ± 13 | 61 ± 11 |
| Body mass index (kg/m2) | 24.4 ± 2.3 | 28.9 ± 3.7 | 26.0 ± 5.6 |
| Plasma C-reactive protein (mg/L) | 1.4 (0.9–4) | 234 (106–450) | 9 (0.9–44) |
| Plasma albumin (g/L) | 39.0 ± 2.0 | 26.0 ± 4.6 | 32.8 ± 6.8 |
| White blood cell count (109/L) | 6.2 ± 0.9 | 13.0 ± 5.0 | 7.0 ± 2.3 |
| Platelet count (109/L) | 232 ± 30 | 232 ± 66 | 316 ± 120 |
| Prothrombin time, INRb | 1.0 ± 0.1 | 1.1 ± 0.2 | |
| Plasma creatinine (μmol/L) | 71 ± 14 | 83 ± 26 | 71 ± 17 |
Data presented as mean ± standard deviation or median (range) as appropriate according to Shapiro-Wilk’s test of normality
aBaseline measurements
bInternational normalized ratio (INR), no units, normal range 0.8–1.2