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. 2016 Nov 16;16:459. doi: 10.1186/s12906-016-1390-8

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Effect of GR on levels of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF- $α$ ) in DSS-induced colitis. Ulcerative colitis was induced and GR and 5-ASA administered as described in the legend to Fig. 1. Cytokine production was determined by ELISA. a IL-6 production in mouse serum at day 10. b TNF-α production in mouse serum at day 10. c IL-6 production in colon tissue. d TNF-α production in colon tissue. Values represent mean ± S.E.M. ( $n$ = 6). Data were analyzed by Tukey post hoc test (^# $P$ < 0.05 versus control and ^* $P$ < 0.05 versus DSS alone)