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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Methods Mol Biol. 2017;1468:91–109. doi: 10.1007/978-1-4939-4035-6_8

Figure 4.

Figure 4

Schematic representation of the workflow of enhancer detection. Peaks are called by MACS. Mapping/annotation to nearest gene is executed by Cisgenome. Distance based parsing is performed to categorize the peaks to enhancers and promoters. Enhancers are divided into extragenic and intragenic to prevent clouding of downstream analysis. Further filtration is performed to remove promoters, unannotated genes, and non-coding RNAs.