FIG 1 .

Carboxylic acids support robust extracellular alkalinization. The wild-type SC5314 strain was grown on minimal YNB medium containing 10 mM of the indicated compound as the sole carbon source at 37°C for 24 h, monitoring growth (by optical density) (A, C) and the pH of the culture medium (using a pH probe) (B, D). (A) Growth of C. albicans in medium with glucose, Casamino Acids, glutamate, or α-ketoglutarate. (B) pHs of the cultures whose growth is shown in panel A. (C) Other carboxylic acids also support neutralization, including pyruvate, acetate, and lactate. (D) pHs of the cultures whose growth is shown in panel C. Error bars show standard deviations.