Table 4. Integrated and average fasting hormone values (mean ± s.e.) over both study days in NW and OB children.
Normal weight | Obese | P | |
---|---|---|---|
Integrateda | |||
nsulin (μU/ml) | 170 ± 12 | 452 ± 71 | < 0.001 |
PYY (pg/ml) | 1,176 ± 88 | 1,350 ± 106 | 0.21 |
Leptin (ng/ml) | 39 ± 7 | 229 ± 41 | < 0.001 |
Ghrelin (pg/ml) | 264 ± 22 | 191 ± 22 | 0.027 |
Average fastingb | |||
Insulin (μU/ml) | 20.2 ± 1.4 | 38.5 ± 4.3 | < 0.001 |
PYY (pg/ml) | 235 ± 19 | 277 ± 31 | 0.25 |
Leptin (ng/ml) | 8.9 ± 1.6 | 51.9 ± 8.7 | < 0.001 |
Ghrelin (pg/ml) | 66.0 ± 5.1 | 55.1 ± 7.9 | 0.26 |
Data were compared by unpaired two-tailed t-test. N = 15–17 for all data indicated and include those subjects for whom all samples on both study days were suitable for analyses (a few samples were not adequate due to insufficient volume).
NW, normal weight; OB, obese.
Summation of pre-meal and pre-bedtime snack values for each child on each day (8 values per child).
Average of two pre-breakfast values.