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. 2016 Nov 7;95(1-2):518–526. doi: 10.1002/jnr.23850

Figure 2.

Figure 2

LTP is reduced in αNOS1 knockouts in a sex‐specific manner. A: LTP is reduced in αNOS1 knockouts compared with wild types (WTs; sexes combined). B: Male and female WTs showed similar magnitudes of LTP. C: Male αNOS1s show no significant LTP, whereas female αNOS1 knockouts do show LTP. L‐NNA has no effect on LTP in female αNOS1 knockouts (D) or male αNOS1 knockouts (E), which already lack LTP. F: Average level of potentiation observed at 60 min, showing within‐group significance (††P < 0.01, †††P < 0.001, paired t‐test) and comparisons between genotypes or sexes (*P < 0.05, **P < 0.01, ***P < 0.005). Scale bar = 100 msec/5 mV for example paired pulse EPSPs. Reproduced from the Journal of Neuroscience Dachtler et al. (2012) with permission.