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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Immunol Rev. 2016 Nov;274(1):330–353. doi: 10.1111/imr.12499

Figure 4. Definition of Septic Shock and Associated Mortality.

Figure 4

Septic shock is now defined as a subset of sepsis in which profound circulatory, cellular, and metabolic abnormalities are associated with a greater risk of mortality than with sepsis alone. Clinically, patients with septic shock can be identified by a vasopressor requirement to maintain a mean arterial pressure of 65 mmHg or greater and serum lactate level greater than 2 mmol/L (>18mg/dL) in the absence of hypovolemia with in-hospital mortality rates greater than 40%.